Copper transport to the brain by the blood-brain barrier and blood-CSF barrier

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Copper transport to the brain by the blood-brain barrier and blood-CSF barrier.

The mechanism of copper (Cu) transport into the brain is unclear. This study evaluated the main species and route of Cu transport into the brain using in situ brain perfusion technique, and assessed the levels of mRNA encoding Cu transporters using real time RT-PCR. Free (64)Cu uptake in rat choroid plexus (CP), where the blood-cerebrospinal fluid barrier (BCB) is primarily located, is about 50...

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ژورنال

عنوان ژورنال: Brain Research

سال: 2009

ISSN: 0006-8993

DOI: 10.1016/j.brainres.2008.10.056